sufentanil 250 mcg

The incidence and severity of muscle rigidity is dose related. No such dose change is recommended for women. We comply with the HONcode standard for trustworthy health information - Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products.

Use of sodium oxybate with alcohol or sedative hypnotics is contraindicated.Stiripentol: May increase the serum concentration of CYP3A4 Substrates (High risk with Inhibitors). Management: Use caution if coadministering blonanserin and CNS depressants; dose reduction of the other CNS depressant may be required. May also administer doses in the range of 5 to 20 mcg as needed (Barash 2009) Continuous infusion: May also be administered as a continuous infusion with the infusion rate based on the induction dose used. Specifically, the risk for serotonin syndrome or opioid toxicities (eg, respiratory depression, coma) may be increased. Monitor for respiratory depression, especially during initiation of sufentanil.Sufentanil exposes users to risks of addiction, abuse, and misuse, which can lead to overdose and death.

Use of suvorexant with alcohol is not recommended, and the use of suvorexant with any other drug to treat insomnia is not recommended.Terlipressin: May enhance the bradycardic effect of Bradycardia-Causing Agents.Tetrahydrocannabinol: May enhance the CNS depressant effect of CNS Depressants.Tetrahydrocannabinol and Cannabidiol: May enhance the CNS depressant effect of CNS Depressants.Thalidomide: CNS Depressants may enhance the CNS depressant effect of Thalidomide. ... 100 mcg/2 mL (2 mL); 250 mcg/5 mL (5 mL) Tablet Sublingual, Sublingual, as citrate: Dsuvia: 30 mcg [contains fd&c blue #2 (indigotine)] Brand Names: U.S. Dsuvia; Pharmacologic Category. Management: If this combination cannot be avoided, monitor patients for evidence of symptomatic bradycardia, and closely monitor blood pressure and heart rate during therapy. Erdafitinib: May increase the serum concentration of CYP3A4 Substrates (High risk with Inhibitors).Fexinidazole [INT]: Bradycardia-Causing Agents may enhance the arrhythmogenic effect of Fexinidazole [INT]. Blonanserin: CNS Depressants may enhance the CNS depressant effect of Blonanserin. High doses of pancuronium may produce increases in heart rate during sufentanil-oxygen anesthesia. Follow patients closely for signs and symptoms of respiratory depression, sedation, and hypotension. Methotrimeprazine may enhance the CNS depressant effect of CNS Depressants. Retain in carton until time of use.Distributed by Hospira, Inc., Lake Forest, IL 60045 USAThe easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Management: Consider dose reductions of droperidol or of other CNS agents (eg, opioids, barbiturates) with concomitant use. It is not known whether these effects on fertility are reversible The safety and efficacy of intravenous sufentanil in pediatric patients as young as 1 day old undergoing cardiovascular surgery have been documented in a limited number of cases.

Monitor patients receiving sufentanil and any CYP3A4 inhibitor or inducer.Concomitant use of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death. Use of suvorexant with alcohol is not recommended, and the use of suvorexant with any other drug to treat insomnia is not recommended.Terlipressin: May enhance the bradycardic effect of Bradycardia-Causing Agents.Tetrahydrocannabinol: May enhance the CNS depressant effect of CNS Depressants.Tetrahydrocannabinol and Cannabidiol: May enhance the CNS depressant effect of CNS Depressants.Thalidomide: CNS Depressants may enhance the CNS depressant effect of Thalidomide. after administration of a single dose of 50 mcg epidural sufentanil during delivery, then impaired neonatal adaption to sound and light can be detected for 1 to 4 hours and if a dose of 80 mcg is used impaired neuromuscular coordination can be detected for more than 4 hours.Sufentanil Citrate Injection, USP equivalent to 50 mcg/mL sufentanil is supplied in the following single-use containers:Protect from light. May contain sodium hydroxide and/or hydrochloric acid for pH adjustment. In all cases sufentanil was administered following a dose of local anesthetic to test proper catheter placement. Consider use of lean body weight for dosing in patients >20% over ideal body weight.• Prostatic hyperplasia/urinary stricture: Use opioids with caution in patients with prostatic hyperplasia and/or urinary stricture.• Psychosis: Use opioids with caution in patients with toxic psychosis.• Renal impairment: Use with caution and reduce dose as needed in patients with renal impairment.• Respiratory disease: Use with caution and monitor for respiratory depression in patients with significant chronic obstructive pulmonary disease or cor pulmonale, and those with a substantially decreased respiratory reserve, hypoxia, hypercapnia, or preexisting respiratory depression, particularly when initiating and titrating therapy; critical respiratory depression may occur, even at therapeutic dosages.• Seizures: Use with caution in patients with a history of seizure disorders; may increase risk or exacerbate preexisting seizure disorders.• Sleep-related disorders: Opioid use increases the risk for sleep-related disorders (eg, central sleep apnea, hypoxemia) in a dose-dependent fashion; use with caution.• Thyroid dysfunction: Use opioids with caution in patients with thyroid dysfunction.• Benzodiazepines or other CNS depressants: Concomitant use of opioids with benzodiazepines or other CNS depressants, including alcohol, may result in hypotension, profound sedation, respiratory depression, coma, and death.

Management: Alvimopan is contraindicated in patients receiving therapeutic doses of opioids for more than 7 consecutive days immediately prior to alvimopan initiation.Amifostine: Blood Pressure Lowering Agents may enhance the hypotensive effect of Amifostine. Total dose should not exceed 1 mcg/kg/hour of expected surgical time.Continuous infusion: May also be administered as a continuous infusion with the infusion rate based on the induction dose used. Overall, the effects of opioids appear to be modestly immunosuppressive.The minimum effective analgesic concentration will vary widely among patients, especially among patients who have been previously treated with potent agonist opioids There is a relationship between increasing sufentanil plasma concentration and increasing frequency of dose-related opioid adverse reactions such as nausea, vomiting, CNS effects, and respiratory depression.

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